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Ingenuity Pathway Analysis (IPA) Training

Ingenuity Pathway Analysis (IPA) Training In-Person / Online

Tufts University Users should follows these instructions to set up their IPA account before attending the workshop:

https://it.tufts.edu/research-technology/bioinformatics/ingenuity-pathway-analysis

Part I: Navigating the IPA knowledgebase (BKB): Query and visualize molecular-phenotypic interactions 

  • Overview of the Biomedical Knowledge Base
  • Generate a network for genes, chemicals and diseases 
    • Activity prediction for hypothesis generation and experiment design
    • Project searching

Part II: Core Analysis of user Omics data (gene/transcript/protein or metabolite)

  • Preparing your data for upload
    • Dataset and file formats
    • Settings and options for configuring a core analysis
  • Paradigms for data reduction and biological interpretation in the core analysis
    • Biological mechanisms, regulators and targets
    • Compare across groups (time points, treatments, sc clusters etc.)
    • Activity heatmap for pathways, regulators and bio functions
    • Compare contrast activity of pathways, bio. functions and regulators
    • Discover condition-specific biomarkers 
  • Functional comparisons of user data with published data
    • Analysis Match, activity plot, patter search
    • Heatmaps, hierarchical clustering

Part III: Surveillance of Public Data with Land Explorer

  • (GEO, SRA, TCGA etc.) 
    • Investigate a gene/biomarker’s expression across diseases, tissues, cell types etc.
    • Derive gene/biomarker signatures for condition of interest (ex. treatment, disease subtype, cell type etc.)
  • Searching and interpretation of published expression analyses
    • Search and open pathway analyses of public datasets
    • Study biological mechanisms and discover key regulators/drug targets
Date:
Wednesday, September 28, 2022
Time:
9:00am - 12:00pm
Time Zone:
Eastern Time - US & Canada (change)
Location:
574 Boston 310
Campus:
Medford
Categories:
  Bioinformatics Workshop  
Registration has closed.

Event Organizer

Profile photo of Adelaide Rhodes
Adelaide Rhodes

Senior Bioinformatics Scientist

Research Technology 

TTS